Changes

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Line 4,086: Line 4,086:  
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==WHO Breast tumours  (5th ed.) Content==
 
==WHO Breast tumours  (5th ed.) Content==
 
{| class="wikitable"
 
{| class="wikitable"
Line 4,097: Line 4,098:  
!'''Date of Last Editor Review'''
 
!'''Date of Last Editor Review'''
 
!'''Notes'''
 
!'''Notes'''
|-|Astrocytoma, IDH-mutant||Disease||
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|-|Usual ductal hyperplasia||Disease||
 
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|Oligodendroglioma, IDH-mutant and 1p/19q-codeleted||Disease||
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|Columnar cell lesions, including flat epithelial atypia ||Disease||
 
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|Glioblastoma, IDH-wildtype||Disease||
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|Atypical ductal hyperplasia||Disease||
 
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|Diffuse astrocytoma, MYB- or MYBL1-altered||Disease||
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|Sclerosing adenosis||Disease||
 
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|Angiocentric glioma||Disease||
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|Apocrine adenosis and adenoma||Disease||
 
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|Polymorphous low-grade neuroepithelial tumour of the young||Disease||
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|Microglandular adenosis ||Disease||
 
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|Diffuse low-grade glioma, MAPK pathway-altered ||Disease||
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|Radial scar / complex sclerosing lesion ||Disease||
 
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|Diffuse midline glioma, H3 K27-altered||Disease||
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|Tubular adenoma ||Disease||
 
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|Diffuse hemispheric glioma, H3 G34-mutant||Disease||
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|Lactating adenoma ||Disease||
 
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|-
|Diffuse paediatric-type high-grade glioma, H3-wildtype and IDH-wildtype||Disease||
+
|Ductal adenoma||Disease||
 
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|Infant-type hemispheric glioma||Disease||
+
|Pleomorphic adenoma||Disease||
 
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|Pilocytic astrocytoma ||Disease||
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|Adenomyoepithelioma||Disease||
 
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Line 4,205: Line 4,206:  
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|-
|High-grade astrocytoma with piloid features||Disease||
+
|Malignant adenomyoepithelioma||Disease||
 
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Line 4,214: Line 4,215:  
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|Pleomorphic xanthoastrocytoma||Disease||
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|Intraductal papilloma||Disease||
 
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|-
|Subependymal giant cell astrocytoma||Disease||
+
|Papillary ductal carcinoma in situ||Disease||
 
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|Chordoid glioma||Disease||
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|Encapsulated papillary carcinoma||Disease||
 
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|-
|Astroblastoma, MN1-altered||Disease||
+
|Solid papillary carcinoma (in situ and invasive)||Disease||
 
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|-
|Ganglioglioma||Disease||
+
|Invasive papillary carcinoma||Disease||
 
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|-
|Gangliocytoma||Disease||
+
|Atypical lobular hyperplasia ||Disease||
 
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|-
 
|-
|Desmoplastic infantile ganglioglioma / desmoplastic infantile astrocytoma||Disease||
+
|Lobular carcinoma in situ||Disease||
 
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|Dysembryoplastic neuroepithelial tumour||Disease||
+
|Ductal carcinoma in situ ||Disease||
 
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|-
 
|-
|Diffuse glioneuronal tumour with oligodendroglioma-like features and nuclear clusters||Disease||
+
|Invasive breast carcinoma: General overview||Disease||
 
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|Papillary glioneuronal tumour||Disease||
+
|Invasive breast carcinoma of no special type||Disease||
 
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|-
|Rosette-forming glioneuronal tumour||Disease||
+
|Microinvasive carcinoma||Disease||
 
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|-
|Myxoid glioneuronal tumour||Disease||
+
|Invasive lobular carcinoma ||Disease||
 
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|-
 
|-
|Diffuse leptomeningeal glioneuronal tumour||Disease||
+
|Tubular carcinoma||Disease||
 
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|
 
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|-
 
|-
|Multinodular and vacuolating neuronal tumour||Disease||
+
|Cribriform carcinoma||Disease||
 
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|-
 
|-
|Dysplastic cerebellar gangliocytoma (Lhermitte-Duclos disease)||Disease||
+
|Mucinous carcinoma||Disease||
 
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|-
|Central neurocytoma||Disease||
+
|Mucinous cystadenocarcinoma||Disease||
 
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|-
 
|-
|Extraventricular neurocytoma||Disease||
+
|Invasive micropapillary carcinoma||Disease||
 
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|-
|Cerebellar liponeurocytoma||Disease||
+
|Carcinoma with apocrine differentiation||Disease||
 
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|-
|Supratentorial ependymoma||Disease||
+
|Metaplastic carcinoma||Disease||
 
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|-
|Supratentorial ependymoma, ZFTA fusion-positive ||Disease||
+
|Acinic cell carcinoma||Disease||
 
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|-
|Supratentorial ependymoma, YAP1 fusion-positive||Disease||
+
|Adenoid cystic carcinoma||Disease||
 
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|-
|Posterior fossa ependymoma||Disease||
+
|Secretory carcinoma ||Disease||
 
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|-
|Posterior fossa group A (PFA) ependymoma||Disease||
+
|Mucoepidermoid carcinoma||Disease||
 
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|-
|Posterior fossa group B (PFB) ependymoma||Disease||
+
|Polymorphous adenocarcinoma||Disease||
 
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|-
 
|-
|Spinal ependymoma||Disease||
+
|Tall cell carcinoma with reversed polarity||Disease||
 
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|-
 
|-
|Spinal ependymoma, MYCN-amplified||Disease||
+
|Neuroendocrine tumour||Disease||
 
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|-
 
|-
|Myxopapillary ependymoma||Disease||
+
|Neuroendocrine carcinoma||Disease||
 
|
 
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|
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|-
 
|-
|Subependymoma||Disease||
+
|Hamartoma ||Disease||
 
|
 
|
 
|
 
|
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|-
 
|-
|Choroid plexus papilloma||Disease||
+
|Fibroadenoma ||Disease||
 
|
 
|
 
|
 
|
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|-
 
|-
|Atypical choroid plexus papilloma||Disease||
+
|Phyllodes tumour ||Disease||
 
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Line 4,484: Line 4,485:  
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|-
 
|-
|Choroid plexus carcinoma||Disease||
+
|Syringomatous tumour ||Disease||
 
|
 
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|
Line 4,493: Line 4,494:  
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|-
 
|-
|Medulloblastoma, WNT-activated||Disease||
+
|Nipple adenoma ||Disease||
 
|
 
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|
 
|
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|-
 
|-
|Medulloblastoma, SHH-activated and TP53-wildtype||Disease||
+
|Paget disease of the breast||Disease||
 
|
 
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|
 
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|-
|Medulloblastoma, SHH-activated and TP53-mutant||Disease||
+
|Haemangioma||Disease||
 
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|Medulloblastoma, non-WNT/non-SHH||Disease||
+
|Angiomatosis||Disease||
 
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|-
 
|-
|Medulloblastoma, histologically defined||Disease||
+
|Atypical vascular lesions ||Disease||
 
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|-
 
|-
|Atypical teratoid/rhabdoid tumour||Disease||
+
|Postradiation angiosarcoma of the breast||Disease||
 
|
 
|
 
|
 
|
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|
 
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|-
 
|-
|Cribriform neuroepithelial tumour||Disease||
+
|Primary angiosarcoma of the breast||Disease||
 
|
 
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|
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|
 
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|-
 
|-
|Embryonal tumour with multilayered rosettes||Disease||
+
|Nodular fasciitis||Disease||
 
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|-
 
|-
|CNS neuroblastoma, FOXR2-activated||Disease||
+
|Myofibroblastoma||Disease||
 
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|-
 
|-
|CNS tumour with BCOR internal tandem duplication||Disease||
+
|Desmoid fibromatosis ||Disease||
 
|
 
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|CNS embryonal tumour NEC/NOS||Disease||
+
|Inflammatory myofibroblastic tumour ||Disease||
 
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|-
|Pineocytoma||Disease||
+
|Schwannoma ||Disease||
 
|
 
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|
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|
 
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|-
|Pineal parenchymal tumour of intermediate differentiation||Disease||
+
|Neurofibroma ||Disease||
 
|
 
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Line 4,610: Line 4,611:  
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|-
|Pineoblastoma||Disease||
+
|Granular cell tumour||Disease||
 
|
 
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Line 4,619: Line 4,620:  
|
 
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|-
|Papillary tumour of the pineal region||Disease||
+
|Leiomyoma||Disease||
 
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|
Line 4,628: Line 4,629:  
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|-
 
|-
|Desmoplastic myxoid tumour of the pineal region, SMARCB1-mutant||Disease||
+
|Leiomyosarcoma ||Disease||
 
|
 
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|
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|-
|Schwannoma||Disease||
+
|Lipoma ||Disease||
 
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|-
|Neurofibroma||Disease||
+
|Angiolipoma ||Disease||
 
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|-
|Perineurioma||Disease||
+
|Liposarcoma ||Disease||
 
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|-
|Hybrid nerve sheath tumours||Disease||
+
|Pseudoangiomatous stromal hyperplasia||Disease||
 
|
 
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|-
|Malignant melanotic nerve sheath tumour||Disease||
+
|Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma)||Disease||
 
|
 
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|
 
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|-
|Malignant peripheral nerve sheath tumour||Disease||
+
|Follicular lymphoma ||Disease||
 
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|-
|Cauda equina neuroendocrine tumour (previously paraganglioma)||Disease||
+
|Diffuse large B-cell lymphoma ||Disease||
 
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|Meningioma||Disease||
+
|Burkitt lymphoma||Disease||
 
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|Solitary fibrous tumour||Disease||
+
|Breast implant-associated anaplastic large cell lymphoma ||Disease||
 
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|Haemangiomas and vascular malformations||Disease||
+
|Gynaecomastia||Disease||
 
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|-
|Haemangioblastoma||Disease||
+
|Carcinoma in situ||Disease||
 
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|Rhabdomyosarcoma||Disease||
+
|Invasive carcinoma||Disease||
 
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|Intracranial mesenchymal tumour, FET::CREB fusion-positive||Disease||
+
|Metastases to the breast||Disease||
 
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|CIC-rearranged sarcoma||Disease||
+
|BRCA1/2-associated hereditary breast and ovarian cancer syndrome||Disease||
 
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|Primary intracranial sarcoma, DICER1-mutant||Disease||
+
|Cowden syndrome||Disease||
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|Ewing sarcoma||Disease||
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|Mesenchymal chondrosarcoma||Disease||
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|Chondrosarcoma||Disease||
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|Chordoma||Disease||
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|-
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|Diffuse meningeal melanocytic neoplasms: Melanocytosis and melanomatosis||Disease||
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|Circumscribed meningeal melanocytic neoplasms: Melanocytoma and melanoma||Disease||
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|Primary diffuse large B-cell lymphoma of the CNS||Disease||
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|-
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|Immunodeficiency-associated CNS lymphomas||Disease||
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|-
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|Lymphomatoid granulomatosis||Disease||
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|-
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|Intravascular large B-cell lymphoma||Disease||
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|-
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|MALT lymphoma of the dura||Disease||
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|-
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|Other low-grade B-cell lymphomas of the CNS||Disease||
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|Anaplastic large cell lymphoma (ALK+/ALK−)||Disease||
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|-
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|T-cell and NK/T-cell lymphomas||Disease||
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|Erdheim-Chester disease||Disease||
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|-
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|Rosai-Dorfman disease||Disease||
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|-
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|Juvenile xanthogranuloma||Disease||
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|-
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|Langerhans cell histiocytosis||Disease||
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|-
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|Histiocytic sarcoma||Disease||
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|Germ cell tumours of the CNS||Disease||
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|-
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|Adamantinomatous craniopharyngioma||Disease||
   
|
 
|
 
|
 
|
Line 4,961: Line 4,773:  
|
 
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|-
|Papillary craniopharyngioma||Disease||
+
|Ataxia-telangiectasia||Disease||
 
|
 
|
 
|
 
|
Line 4,970: Line 4,782:  
|
 
|
 
|-
 
|-
|Pituicytoma, granular cell tumour of the sellar region, and spindle cell oncocytoma||Disease||
+
|Li-Fraumeni syndrome, TP53-associated||Disease||
 
|
 
|
 
|
 
|
Line 4,979: Line 4,791:  
|
 
|
 
|-
 
|-
|Pituitary adenoma / pituitary neuroendocrine tumour||Disease||
+
|Li-Fraumeni syndrome, CHEK2-associated||Disease||
 
|
 
|
 
|
 
|
Line 4,988: Line 4,800:  
|
 
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|-
 
|-
|Pituitary blastoma||Disease||
+
|CDH1-associated breast cancer||Disease||
 
|
 
|
 
|
 
|
Line 4,997: Line 4,809:  
|
 
|
 
|-
 
|-
|Metastases to the brain and spinal cord parenchyma||Disease||
+
|PALB2-associated cancers||Disease||
 
|
 
|
 
|
 
|
Line 5,006: Line 4,818:  
|
 
|
 
|-
 
|-
|Metastases to the meninges||Disease||
+
|Peutz-Jeghers syndrome||Disease||
 
|
 
|
 
|
 
|
Line 5,024: Line 4,836:  
|
 
|
 
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|-
|Neurofibromatosis type 2||Disease||
+
|}
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|-
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|Schwannomatosis||Disease||
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|-
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|Von Hippel-Lindau syndrome||Disease||
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  −
|-
  −
|Tuberous sclerosis||Disease||
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|-
  −
|Li-Fraumeni syndrome||Disease||
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|-
  −
|Cowden syndrome||Disease||
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|-
  −
|Constitutional mismatch repair deficiency syndrome||Disease||
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|-
  −
|Familial adenomatous polyposis 1||Disease||
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|-
  −
|Naevoid basal cell carcinoma syndrome||Disease||
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|-
  −
|Rhabdoid tumour predisposition syndrome||Disease||
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|-
  −
|Carney complex||Disease||
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|-
  −
|DICER1 syndrome||Disease||
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|-
  −
|Familial paraganglioma syndromes||Disease||
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|-
  −
|Melanoma-astrocytoma syndrome||Disease||
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|-
  −
|Familial retinoblastoma||Disease||
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|-
  −
|BAP1 tumour predisposition syndrome||Disease||
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|-
  −
|Fanconi anaemia||Disease||
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|-
  −
|ELP1-medulloblastoma syndrome||Disease||
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|
  −
|-
  −
}