Difference between revisions of "The Compendium of Cancer Genome Aberrations"

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'''Welcome to the Compendium of Cancer Genome Aberrations (CCGA)! The CCGA is a collaborative effort to document and describe clinically relevant chromosome and other genomic abnormalities in cancer structured based on [https://tumourclassification.iarc.who.int/welcome/ current WHO classification] as published by [https://whobluebooks.iarc.fr/about/ IARC]. The Wiki style interface allows for real-time editing and content sharing within our genetics community. This resource is sponsored and supported by the [http://www.cancergenomics.org <u>Cancer Genomics Consortium (CGC)</u>] and contributed to by colleagues with an interest in clinical cytogenetics, molecular genetics and genomics in cancer.'''
  
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*Join the CCGA community!  If you would like to contribute as an '''<u>[[Description of CCGA Roles|Author or Other Role]]</u>''', please complete a few brief questions on our '''[https://mms.cancergenomics.org/members/form.php?orgcode=CGC&fid=3830649 <u>Volunteer Form</u>]'''.  We are creating content for all diseases with genetic findings in the current WHO Classification of Tumours books. [[Volunteer Assignments and Opportunities|'''<u>Please join the effort by looking through the authorship opportunities</u>''']]!
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'''<big>Compendium of Cancer Genome Aberrations (CCGA) is collaborative project to document and describe chromosome and other genomic abnormalities in cancer. This resource is supported by the [http://www.cancergenomics.org Cancer Genomics Consortium (CGC)] and others with an interest in clinical cytogenetics, molecular genetics and genomics in cancer. [[Contact us]] for more information.</big>'''
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*'''[Mailto:CCGA@cancergenomics.org <u>Contact us</u>]''' for more information or suggestions for updates.
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*Meet our '''<u>[[Leadership|Editorial Leadership]]</u>''', '''<u>[[CCGA Workgroup|CCGA Workgroup Members]]</u>''' and [[Communications Liaison|<u>'''Communications Liaison'''</u>]].
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*For contributors, we've created a '''<u>[[Video_Tutorial|Video Tutorial]]</u>''' demonstrating how to add content to the CCGA. Please also refer to helpful '''<u>[[Author Instructions|Author Instructions]]</u>'''.
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*Become a part of our Twitter family for the latest updates [https://twitter.com/ccgawiki '''@ccgawiki'''].
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[[File:Generic book cover heme and lymphoid.jpg|thumb|link=HAEM5:Table_of_Contents|Search content structured based on the WHO Classification ('''click book image'''). ''Reference: WHO Classification of Tumours Editorial Board. [https://tumourclassification.iarc.who.int/chapters/63 Haematolymphoid tumours] [Internet; beta version ahead of print]. Lyon (France): International Agency for Research on Cancer; 2022. The hierarchical tumour classification structure is reproduced from the [https://tumourclassification.iarc.who.int/welcome/ WHO Classification of Tumours] with permission from the copyright holder, ©International Agency for Research on Cancer.''|alt=]]
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[[File:Inv 16 pathology.png |100px|link=:Category:Diseases]] '''Diseases''' '''[[:Category:Diseases A|A]]'''
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| '''[[:Category:Diseases B|B]]''' | '''[[:Category:Diseases C|C]]''' | '''[[:Category:Diseases D|D]]''' | '''[[:Category:Diseases E|E]]''' | '''[[:Category:Diseases F|F]]'''
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| '''[[:Category:Diseases G|G]]''' | '''[[:Category:Diseases H|H]]''' | '''[[:Category:Diseases I|I]]''' | '''[[:Category:Diseases J|J]]''' | '''[[:Category:Diseases K|K]]''' | '''[[:Category:Diseases L|L]]''' | '''[[:Category:Diseases M|M]]''' | '''[[:Category:Diseases N|N]]''' | '''[[:Category:Diseases O|O]]''' | '''[[:Category:Diseases P|P]]''' | '''[[:Category:Diseases Q|Q]]''' | '''[[:Category:Diseases R|R]]''' | '''[[:Category:Diseases S|S]]''' | '''[[:Category:Diseases T|T]]''' | '''[[:Category:Diseases U|U]]'''
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| '''[[:Category:Diseases V|V]]''' | '''[[:Category:Diseases W|W]]''' | '''[[:Category:Diseases X|X]]''' | '''[[:Category:Diseases Y|Y]]''' | '''[[:Category:Diseases Z|Z]]'''
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[[File:Fish_zoomed.png|100px|link=:Category:Cancer Genes]] '''Cancer Genes''' '''[[:Category:Cancer Genes A|A]]'''
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| '''[[:Category:Cancer Genes B|B]]''' | '''[[:Category:Cancer Genes C|C]]''' | '''[[:Category:Cancer Genes D|D]]''' | '''[[:Category:Cancer Genes E|E]]''' | '''[[:Category:Cancer Genes F|F]]'''
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| '''[[:Category:Cancer Genes G|G]]''' | '''[[:Category:Cancer Genes H|H]]''' | '''[[:Category:Cancer Genes I|I]]''' | '''[[:Category:Cancer Genes J|J]]''' | '''[[:Category:Cancer Genes K|K]]''' | '''[[:Category:Cancer Genes L|L]]''' | '''[[:Category:Cancer Genes M|M]]''' | '''[[:Category:Cancer Genes N|N]]''' | '''[[:Category:Cancer Genes O|O]]''' | '''[[:Category:Cancer Genes P|P]]''' | '''[[:Category:Cancer Genes Q|Q]]''' | '''[[:Category:Cancer Genes R|R]]''' | '''[[:Category:Cancer Genes S|S]]''' | '''[[:Category:Cancer Genes T|T]]''' | '''[[:Category:Cancer Genes U|U]]'''
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| '''[[:Category:Cancer Genes V|V]]''' | '''[[:Category:Cancer Genes W|W]]''' | '''[[:Category:Cancer Genes X|X]]''' | '''[[:Category:Cancer Genes Y|Y]]''' | '''[[:Category:Cancer Genes Z|Z]]'''
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[[File:CGC logo only.png|100px|link=Main_Page]]<span id="fp-span-cgc-pre"> '''CGC Workgroups Recurrent Loci Tables'''</span><span id="fp-span-cgc" style="display: block; margin-top: -62px; margin-left: 385px;"> [[AML Table: Recurrent Genomic Alterations Detected by Chromosomal Microarray|AML]] | [[MDS, MDS/MPN and MPN Tables: Recurrent Genomic Alterations Detected by Chromosomal Microarray|MDS/MPN]] | [[CLL Tables: Regions of Recurrent Copy Number Change and CN-LOH|CLL]] | [[Recurrent Genomic Alterations in Pediatric and Adult Central Nervous System Tumors Detected by Chromosomal Microarray|CNS Tumors]] | [[Plasma Cell Neoplasms Tables: Recurrent Cytogenomic Alterations|Plasma Cell Neoplasms]] | [[Breast Cancer Table: Recurrent Genomic Alterations Detected by Chromosomal Microarray|Breast Cancer]] | [[Renal Cell Neoplasia Tables: Recurrent Cytogenomic Alterations|Renal Neoplasia]] | [[B-ALL Tables: Prognostic Genomic Abnormalities and Recurrent Gene Fusions|B-ALL]]</span>
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<h4>[[Translocations et al. in Hematological Cancers|Chromosome Abnormalities]]</h4>
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<h4>[[Submit an Article]]</h4>
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Browse chromosome abnormalities found in heamtological, soft tissue and solid tumors
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[[Video Tutorial]]
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[[Acute Myeloid Leukemia (AML) with t(8;21)(q22;q22.1); RUNX1-RUNX1T1|Example Article]]
 
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Learn about common copy number changes detected by chromosomal microarray
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Browse disease sites and their associated genomic abnormalities
 
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Learn about chromosome abnormalities in cancer and associated mechanistic phenomena
 
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Learn about genes linked to cancer causation
 
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Latest revision as of 10:43, 5 March 2024

Welcome to the Compendium of Cancer Genome Aberrations (CCGA)! The CCGA is a collaborative effort to document and describe clinically relevant chromosome and other genomic abnormalities in cancer structured based on current WHO classification as published by IARC. The Wiki style interface allows for real-time editing and content sharing within our genetics community. This resource is sponsored and supported by the Cancer Genomics Consortium (CGC) and contributed to by colleagues with an interest in clinical cytogenetics, molecular genetics and genomics in cancer.

  • Contact us for more information or suggestions for updates.
  • For contributors, we've created a Video Tutorial demonstrating how to add content to the CCGA. Please also refer to helpful Author Instructions.
  • Become a part of our Twitter family for the latest updates @ccgawiki.
 
Search content structured based on the WHO Classification (click book image). Reference: WHO Classification of Tumours Editorial Board. Haematolymphoid tumours [Internet; beta version ahead of print]. Lyon (France): International Agency for Research on Cancer; 2022. The hierarchical tumour classification structure is reproduced from the WHO Classification of Tumours with permission from the copyright holder, ©International Agency for Research on Cancer.


Inv 16 pathology.png Diseases A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z



Fish zoomed.png Cancer Genes A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z


CGC logo only.png CGC Workgroups Recurrent Loci Tables AML | MDS/MPN | CLL | CNS Tumors | Plasma Cell Neoplasms | Breast Cancer | Renal Neoplasia | B-ALL



Notice and Disclaimer/Limitation of Liability of Resource Use

Data and information obtained from the Cancer Genomics Consortium (CGC) and the Compendium of Cancer Genome Aberrations (CCGA) is provided as an educational resource only. These data are provided on an "AS IS" basis, without representation or warranty of any kind, including without limitation the warranties of merchantability, fitness for a particular purpose and non-infringement. Availability of this data and information does not constitute scientific publication. Data and/or information may contain errors or be incomplete.

The CGC, CCGA and all participating entities make no representation or warranty, express or implied, including without limitation any warranties of merchantability or fitness for a particular purpose or warranties as to the identity or ownership of data or information, the quality, accuracy or completeness of data or information, or that the use of such data or information will not infringe any patent, intellectual property or proprietary rights of any party.

The CGC and CCGA shall not be liable for any claim for any and all loss, harm, illness or other damage or injury arising from access to or use of data or information howsoever caused, including without limitation, any direct, indirect, incidental, exemplary, special or consequential damages, even if advised of the possibility of such damages. The data and information obtained from the Cytogenomics Array Group database shall not be used as a substitute for the user's skills, expertise and experience.



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