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WHO Classification of Eye and Orbit Tumours (5th Edition) Content
Disease Page Type Author Date Assigned to Author Target Completion Date Author Content (Pending or Complete) Date Completed by Author Associate Editor Date of Last Editor Review Notes
CHAPTER 2 (TUMOURS OF THE CONJUCTIVA AND CARUNCLE)








Epithelial conjunctival inclusion cyst Disease
Reactive epithelial hyperplasia of the conjunctiva Disease
Papillary and follicular conjunctivitis Disease
Pterygium and pingueculum Disease
Epibulbar choristoma (dermoid; dermolipoma; complex choristoma) Disease
Epibulbar osseous choristoma Disease
Conjunctival squamous cell papilloma Disease
Conjunctival oncocytoma Disease
Hereditary benign intraepithelial dyskeratosis Disease
Conjunctival squamous intraepithelial neoplasia Disease
Conjunctival squamous cell carcinoma Disease
Adenosquamous carcinoma Disease
Benign epithelial melanosis of the conjunctiva Disease
Junctional, compound and subepithelial conjunctival naevi Disease
Inflamed juvenile conjunctival naevus Disease
Blue naevus of the conjunctiva Disease
WNT-activated deep penetrating/plexiform melanocytoma (naevus) Disease
Combined naevus Disease
Conjunctival melanocytic intraepithelial lesions Disease
Conjunctival melanoma Disease
CHAPTER 3 (TUMOURS OF THE EYELID)








Epidermal inclusion cyst Disease
Intratarsal cyst Disease
Phakomatous choristoma Disease
Molluscum contagiosum Disease
Verruca vulgaris Disease
Squamous cell papilloma Disease
Seborrheic keratosis Disease
Inverted follicular keratosis Disease
Actinic keratosis Disease
Basal cell carcinoma Disease
Squamous cell carcinoma Disease
Merkel cell carcinoma Disease
Ductal hidrocystoma Disease
Sebaceous hyperplasia, adenoma, and sebaceoma Disease
Syringoma Disease
Mixed tumour Disease
Tubular adenoma Disease
Syringocystadenoma papilliferum Disease
Pilomatricoma Disease
Trichilemmoma Disease
Sebaceous carcinoma Disease
Adenoid cystic carcinoma Disease
Signet-ring cell/histiocytoid carcinoma Disease
Mucinous carcinoma Disease
Endocrine mucin-producing sweat gland carcinoma Disease
Microcystic adnexal carcinoma Disease
Apocrine carcinoma Disease
Naevi of the eyelid Disease
Spitz naevus Disease
In-situ cutaneous melanoma Disease
Invasive cutaneous melanoma Disease
CHAPTER 4 (TUMOURS OF THE UVEAL TRACT)








Ectopic tissue Disease
Implantation cyst Disease
Pigmented epithelial cyst Disease
Lisch nodule Disease
Ocular melanocytosis Disease
Iris naevus Disease
Iris melanoma Disease
Choroidal and ciliary body naevi Disease
Uveal melanocytoma Disease
Bilateral diffuse uveal melanocytic proliferation Disease
Choroidal and ciliary body melanomas Disease
CHAPTER 5 (TUMOURS OF THE RETINA AND NEUROEPITHELIUM)








Astrocytic tumours Disease
Nodular and massive retinal gliosis Disease
Retinocytoma Disease
Retinoblastoma Disease
Hamartoma of the retinal pigment epithelium Disease
Congenital hypertrophy of the retinal pigment epithelium Disease
Reactive hyperplasia of the retinal pigment epithelium Disease
Adenoma and adenocarcinoma of the retinal pigment epithelium Disease
Reactive epithelial hyperplasia of the ciliary epithelium Disease
Nodular hyperplasia of the ciliary epithelium Disease
Glioneuronal hamartoma of the ciliary body Disease
Adenoma and adenocarcinoma of the ciliary body Disease
Medulloepithelioma of the ciliary body Disease
CHAPTER 6 (TUMOURS OF THE OPTIC DISC AND OPTIC NERVE)








Optic nerve choristoma Disease
Gliomas of the optic nerve Disease
Medulloepithelioma of the optic disc and optic nerve Disease
Meningioma of the optic nerve Disease
Melanocytoma of the optic disc and optic nerve Disease
CHAPTER 7 (TUMOURS OF THE LACRIMAL GLAND)








Dacryops cyst Disease
Pleomorphic adenoma of the lacrimal gland Disease
Lacrimal gland oncocytoma Disease
Myoepithelioma Disease
Intraductal carcinoma Disease
Carcinoma ex pleomorphic adenoma Disease
Adenoid cystic carcinoma Disease
Primary ductal adenocarcinoma of the lacrimal gland Disease
Secretory carcinoma Disease
Mucoepidermoid carcinoma Disease
Epithelial-myoepithelial carcinoma Disease
Acinic cell carcinoma Disease
Adenocarcinoma, NOS Disease
CHAPTER 8 (TUMOURS OF THE LACRIMAL DRAINAGE SYSTEM)








Papillomas (squamous and inverted) Disease
Squamous cell carcinoma Disease
Lymphoepithelial carcinoma Disease
Mucoepidermoid carcinoma Disease
Other salivary gland-type carcinomas of the lacrimal drainage system Disease
Adenocarcinoma NOS of the lacrimal drainage system Disease
Melanoma involving the lacrimal drainage system Disease
CHAPTER 9 (TUMOURS OF THE ORBIT)








Orbital dermoid cysts and other orbital cysts Disease
Cavernous vascular malformation Disease
Combined lymphatic-venous malformation of the orbit Disease
Orbital venous malformation Disease
Arteriovenous malformation Disease
Orbital glial heterotopia Disease
Mesenchymal hamartoma of the orbit Disease
Teratoma Disease
Yolk sac tumour Disease
Primary orbital melanoma Disease
CHAPTER 10 (HAEMATOLYMPHOID TUMOURS)








Reactive lymphoid hyperplasia Disease
IgG4-related disease Disease
Primary choroidal lymphoma Disease
Primary vitreoretinal large B-cell lymphoma Disease
Extranodal marginal zone lymphoma Disease
Follicular lymphoma Disease
Mantle cell lymphoma Disease
Chronic lymphocytic leukaemia/small lymphocytic lymphoma Disease
Diffuse large B-cell lymphoma Disease
Plasmacytoma Disease
CD30 positive lymphoproliferative disorders Disease
T-cell lymphomas Disease
Extranodal lymphoma of mature NK or T-cell lineage Disease
Extramedullary myeloid sarcoma Disease
Juvenile xanthogranuloma Disease
Rosai-Dorfman disease Disease
Erdheim-Chester disease Disease
Langerhans cell tumours Disease
Xanthelasma Disease
Adult orbital xanthogranulomatous disease Disease
CHAPTER 11 (SOFT TISSUE AND BONE TUMOURS)








Conjunctival stromal tumour and ocular surface fibroma Disease
Fibrous histiocytoma Disease
Nodular and proliferative fasciitis, proliferative myositis Disease
Solitary fibrous tumour Disease
Inflammatory myofibroblastic tumour Disease
Dermatofibrosarcoma protuberans Disease
Angiomyxoma Disease
Benign lipomatous tumours Disease
Malignant adipocytic tumours Disease
Rhabdomyosarcoma family Disease
Leiomyoma Disease
Mesectodermal leiomyoma Disease
Leiomyosarcoma Disease
Schwannoma Disease
Neurofibroma Disease
Solitary circumscribed neuroma Disease
Granular cell tumour Disease
Malignant peripheral nerve sheath tumour Disease
Masson tumour Disease
Infantile haemangioma Disease
Lobular capillary haemangioma Disease
Lymphangiectasia Disease
Epithelioid haemangioma Disease
Haemangioblastoma Disease
Angiosarcoma Disease
Glomus tumour Disease
Myopericytoma, including myofibroma Disease
PEComa Disease
Epithelioid sarcoma Disease
Synovial sarcoma Disease
Alveolar soft part sarcoma Disease
Osteoma Disease
Osteoblastoma Disease
Osteosarcoma Disease
Soft tissue chondroma Disease
Mesenchymal chondrosarcoma Disease
Fibrous dysplasia Disease
Haemangioma of bone Disease
Epithelioid haemangioendothelioma Disease
Angiosarcoma of bone Disease
Aneurysmal bone cyst Disease
Giant cell tumour of bone Disease
Ewing sarcoma Disease
CHAPTER 12 (METASTASES TO THE EYE AND SURROUNDING STRUCTURES)








Metastases to ocular adnexal structures Disease
Metastases to intra-ocular structures Disease
CHAPTER 13 (GENETIC TUMOUR SYNDROMES)








Retinoblastoma syndrome Disease
BAP1 tumour predisposition syndrome Disease
Von Hippel Lindau syndrome Disease
Sturge Weber syndrome Disease
Neurofibromatosis type 1 (NF1) Disease
Goldenhar syndrome Disease
Muir-Torre syndrome Disease