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WHO Classification of Female Genital Tumours (5th Edition) Content
Disease Page Type Author Date Assigned to Author Target Completion Date Author Content (Pending or Complete) Date Completed by Author Associate Editor Date of Last Editor Review Notes
CHAPTER 2 (TUMOURS OF THE OVARY)








Serous cystadenoma, adenofibroma, and surface papilloma of the ovary Disease
Serous borderline tumour of the ovary Disease
Low-grade serous carcinoma of the ovary Disease
High-grade serous carcinoma of the ovary Disease
Mucinous cystadenoma and adenofibroma Disease
Mucinous borderline tumour Disease
Mucinous carcinoma of the ovary Disease
Endometrioid cystadenoma and adenofibroma Disease
Endometrioid borderline tumour Disease
Endometrioid carcinoma of the ovary Disease
Clear cell cystadenoma and adenofibroma Disease
Clear cell borderline tumour Disease
Clear cell carcinoma of the ovary Disease
Seromucinous cystadenoma and adenofibroma Disease
Seromucinous borderline tumour Disease
Brenner tumour Disease
Borderline Brenner tumour Disease
Malignant Brenner tumour Disease
Mesonephric-like adenocarcinoma Disease
Undifferentiated and dedifferentiated carcinomas of the ovary Disease
Carcinosarcoma of the ovary Disease
Mixed carcinoma of the ovary Disease
Endometrioid stromal sarcoma of the ovary Disease
Smooth muscle tumours of the ovary Disease
Ovarian myxoma Disease
Adenosarcoma of the ovary Disease
Ovarian fibroma Disease
Thecoma Disease
Luteinized thecoma associated with sclerosing peritonitis Disease
Sclerosing stromal tumour Disease
Microcystic stromal tumour Disease
Signet-ring stromal tumour Disease
Leydig cell tumour Disease
Steroid cell tumour Disease
Ovarian fibrosarcoma Disease
Adult granulosa cell tumour Disease
Juvenile granulosa cell tumour Disease
Sertoli cell tumour Disease
Sex cord tumour with annular tubules Disease
Sertoli-Leydig cell tumour Disease
Sex cord-stromal tumour NOS Disease
Gynandroblastoma Disease
Mature teratoma of the ovary Disease
Immature teratoma of the ovary Disease
Dysgerminoma Disease
Yolk sac tumour Disease
Embryonal carcinoma Disease
Non-gestational choriocarcinoma Disease
Mixed germ cell tumour of the ovary Disease
Struma ovarii Disease
Ovarian carcinoid Disease
Neuroectodermal-type tumours Disease
Monodermal cystic teratoma Disease
Somatic neoplasms arising from teratomas Disease
Gonadoblastoma Disease
Mixed germ cell-sex cord-stromal tumour, unclassified Disease
Rete cystadenoma, adenoma, and adenocarcinoma Disease
Wolffian tumour of the ovary Disease
Solid pseudopapillary tumour Disease
Small cell carcinoma of the ovary, hypercalcaemic type Disease
Wilms tumour Disease
Follicle cyst Disease
Corpus luteum cyst Disease
Large solitary luteinized follicle cyst Disease
Hyperreactio luteinalis Disease
Pregnancy luteoma Disease
Stromal hyperplasia and hyperthecosis Disease
Fibromatosis and massive oedema Disease
Leydig cell hyperplasia Disease
Metastases to the ovary Disease
CHAPTER 3 (ENDOMETRIOSIS AND RELATED CONDITIONS)








Endometriosis and derived tumours Disease
CHAPTER 4 (TUMOURS OF THE PERITONEUM)








Adenomatoid tumour Disease
Well-differentiated papillary mesothelial tumour Disease
Mesothelioma Disease
Serous borderline tumour of the peritoneum Disease
Low-grade serous carcinoma of the peritoneum Disease
High-grade serous carcinoma of the peritoneum Disease
Leiomyomatosis peritonealis disseminata Disease
Desmoid fibromatosis Disease
Calcifying fibrous tumour Disease
Extragastrointestinal stromal tumour Disease
Solitary fibrous tumour of the peritoneum Disease
Endometrioid stromal sarcoma of the peritoneum Disease
Desmoplastic small round cell tumour Disease
Mesothelial hyperplasia Disease
Peritoneal inclusion cysts Disease
Transitional cell metaplasia Disease
Endosalpingiosis of the peritoneum Disease
Histiocytic nodule Disease
Ectopic decidua Disease
Splenosis Disease
Other tumour-like lesions of the peritoneum Disease
Carcinomas and sarcomas metastatic to the peritoneum Disease
Pseudomyxoma peritonei Disease
Gliomatosis Disease
CHAPTER 5 (TUMOURS OF THE FALLOPIAN TUBE)








Serous adenofibroma and papilloma of the fallopian tube Disease
Serous borderline tumour of the fallopian tube Disease
High-grade serous carcinoma of the fallopian tube Disease
Endometrioid carcinoma of the fallopian tube Disease
Carcinosarcoma of the fallopian tube Disease
Paratubal cysts Disease
Tubal hyperplasia Disease
Tubo-ovarian abscess Disease
Salpingitis isthmica nodosa Disease
Metaplastic papillary lesion Disease
Placental site nodule occurring in the fallopian tube Disease
Mucinous metaplasia Disease
Adenosarcoma of the fallopian tube Disease
Teratoma of the fallopian tube Disease
CHAPTER 6 (TUMOURS OF THE BROAD LIGAMENT AND OTHER UTERINE LIGAMENTS)








Leiomyoma of the broad ligament and other uterine ligaments Disease
Adenomyoma of the broad ligament and other uterine ligaments Disease
Adenosarcoma of the broad ligament and other uterine ligaments Disease
Leiomyosarcoma of the broad ligament and other uterine ligaments Disease
Wolffian tumour of the broad ligament and other uterine ligaments Disease
Papillary cystadenoma Disease
Ependymoma Disease
Adrenocortical remnants Disease
CHAPTER 7 (TUMOURS OF THE UTERINE CORPUS)








Endometrial hyperplasia without atypia Disease
Endometrial atypical hyperplasia / endometrioid intraepithelial neoplasia Disease
Endometrioid carcinoma of the uterine corpus Disease
Serous carcinoma of the uterine corpus Disease
Clear cell carcinoma of the uterine corpus Disease
Undifferentiated and dedifferentiated carcinomas of the uterine corpus Disease
Mixed carcinoma of the uterine corpus Disease
Other endometrial carcinomas Disease
Carcinosarcoma of the uterine corpus Disease
Endometrial polyp Disease
Endometrial metaplasia Disease
Arias-Stella reaction of the uterine corpus Disease
Uterine leiomyoma Disease
Intravenous leiomyomatosis Disease
Smooth muscle tumour of uncertain malignant potential of the uterine corpus Disease
Metastasizing leiomyoma Disease
Uterine leiomyosarcoma Disease
Endometrial stromal nodule Disease
Low-grade endometrial stromal sarcoma Disease
High-grade endometrial stromal sarcoma Disease
Undifferentiated uterine sarcoma Disease
Uterine tumour resembling ovarian sex cord tumour Disease
Perivascular epithelioid cell tumour (PEComa) Disease
Inflammatory myofibroblastic tumour Disease
Adenomyoma of the uterine corpus Disease
Atypical polypoid adenomyoma Disease
Adenosarcoma of the uterine corpus Disease
Central primitive neuroectodermal tumour / CNS embryonal tumour Disease
Germ cell tumours of the uterine corpus Disease
CHAPTER 8 (GESTATIONAL TROPHOBLASTIC DISEASE)








Exaggerated placental site reaction Disease
Placental site nodule and plaque Disease
Abnormal (non-molar) villous lesions Disease
Partial hydatidiform mole Disease
Complete hydatidiform mole Disease
Invasive and metastatic hydatidiform moles Disease
Epithelioid trophoblastic tumour Disease
Placental site trophoblastic tumour Disease
Gestational choriocarcinoma Disease
Mixed trophoblastic tumour Disease
CHAPTER 9 (TUMOURS OF THE UTERINE CERVIX)








Squamous metaplasia Disease
Atrophy of the uterine cervix Disease
Squamous intraepithelial lesions of the uterine cervix Disease
Squamous cell carcinoma, HPV-associated, of the uterine cervix Disease
Squamous cell carcinoma, HPV-independent, of the uterine cervix Disease
Endocervical polyp Disease
Mullerian papilloma of the uterine cervix Disease
Nabothian cyst Disease
Tunnel clusters Disease
Microglandular hyperplasia Disease
Lobular endocervical glandular hyperplasia Disease
Diffuse laminar endocervical hyperplasia Disease
Mesonephric remnants and hyperplasia Disease
Arias-Stella reaction of the uterine cervix Disease
Endocervicosis of the uterine cervix Disease
Tuboendometrioid metaplasia Disease
Ectopic prostate tissue Disease
Adenocarcinoma in situ, HPV-associated, of the uterine cervix Disease
Adenocarcinoma, HPV-associated, of the uterine cervix Disease
Adenocarcinoma in situ, HPV-independent, of the uterine cervix Disease
Adenocarcinoma, HPV-independent, gastric type, of the uterine cervix Disease
Adenocarcinoma, HPV-independent, clear cell type, of the uterine cervix Disease
Adenocarcinoma, HPV-independent, mesonephric type, of the uterine cervix Disease
Other adenocarcinomas of the uterine cervix Disease
Carcinosarcoma of the uterine cervix Disease
Adenosquamous and mucoepidermoid carcinomas of the uterine cervix Disease
Adenoid basal carcinoma of the uterine cervix Disease
Carcinoma of the uterine cervix, unclassifiable Disease
Adenomyoma of the uterine cervix Disease
Adenosarcoma of the uterine cervix Disease
Germ cell tumours of the uterine cervix Disease
CHAPTER 10 (TUMOURS OF THE VAGINA)








Squamous papilloma of the vagina Disease
Atrophy of the vagina Disease
Tubulosquamous polyp Disease
Squamous intraepithelial lesions of the vagina Disease
Squamous cell carcinoma, HPV-associated, of the vagina Disease
Squamous cell carcinoma, HPV-independent, of the vagina Disease
Villous adenoma Disease
Mullerian papilloma of the vagina Disease
Vaginal adenosis Disease
Endocervicosis of the vagina Disease
Cysts of the vagina Disease
Adenocarcinoma, HPV-associated, of the vagina Disease
Endometrioid carcinoma of the vagina Disease
Clear cell carcinoma of the vagina Disease
Mucinous carcinoma, gastric type, of the vagina Disease
Mucinous carcinoma, intestinal type, of the vagina Disease
Mesonephric adenocarcinoma of the vagina Disease
Carcinosarcoma of the vagina Disease
Mixed tumour of the vagina Disease
Adenocarcinoma of Skene gland origin Disease
Adenosquamous carcinoma of the vagina Disease
Adenosarcoma of the vagina Disease
Germ cell tumours of the vagina Disease
CHAPTER 11 (TUMOURS OF THE VULVA)








Seborrhoeic keratosis Disease
Condyloma acuminatum Disease
Squamous intraepithelial lesions, HPV-associated, of the vulva Disease
Vulvar intraepithelial neoplasia, HPV-independent Disease
Squamous cell carcinoma, HPV-associated, of the vulva Disease
Squamous cell carcinoma, HPV-independent, of the vulva Disease
Papillary hidradenoma Disease
Chondroid syringoma Disease
Fibroadenoma Disease
Phyllodes tumour Disease
Adenocarcinoma of mammary gland type Disease
Bartholin gland cyst Disease
Bartholin gland hyperplasia, adenoma, and adenomyoma Disease
Bartholin gland carcinomas Disease
Other cysts of the vulva Disease
Paget disease Disease
Carcinomas of sweat gland origin Disease
Adenocarcinoma of intestinal type Disease
Germ cell tumours of the vulva Disease
CHAPTER 12 (NEUROENDOCRINE NEOPLASIA)








Neuroendocrine tumour Disease
Small cell neuroendocrine carcinoma Disease
Large cell neuroendocrine carcinoma Disease
Carcinoma admixed with neuroendocrine carcinoma Disease
CHAPTER 13 (HAEMATOLYMPHOID PROLIFERATIONS AND NEOPLASIA)








Florid reactive lymphoid hyperplasia Disease
Diffuse large B-cell lymphoma Disease
Extranodal marginal zone lymphoma Disease
Follicular lymphoma Disease
Burkitt lymphoma Disease
Myeloid sarcoma Disease
CHAPTER 14 (MESENCHYMAL TUMOURS OF THE LOWER GENITAL TRACT)








Lipoma Disease
Lipoblastoma-like tumour of the vulva Disease
Liposarcoma Disease
Postoperative spindle cell nodule Disease
Fibroepithelial stromal polyp Disease
Prepubertal fibroma Disease
Superficial myofibroblastoma Disease
Myofibroblastoma Disease
Cellular angiofibroma Disease
Angiomyofibroblastoma Disease
Solitary fibrous tumour of the lower genital tract Disease
Dermatofibrosarcoma protuberans Disease
NTRK-rearranged spindle cell neoplasm (emerging) Disease
Kaposi sarcoma Disease
Angiosarcoma Disease
Leiomyoma of the lower genital tract Disease
Smooth muscle tumour of uncertain malignant potential of the lower genital tract Disease
Leiomyosarcoma of the lower genital tract Disease
Rhabdomyoma Disease
Rhabdomyosarcoma Disease
Benign peripheral nerve sheath tumours Disease
Granular cell tumour Disease
Superficial angiomyxoma Disease
Deep (aggressive) angiomyxoma Disease
Epithelioid sarcoma Disease
Alveolar soft part sarcoma Disease
Ewing sarcoma Disease
CHAPTER 15 (MELANOCYTIC LESIONS)








Acquired melanocytic naevus Disease
Congenital melanocytic naevus Disease
Blue naevus Disease
Atypical melanocytic naevus of genital type Disease
Dysplastic melanocytic naevus Disease
Mucosal melanoma Disease
CHAPTER 16 (METASTASIS)








Metastasis to the lower female genital tract Disease
CHAPTER 17 (GENETIC TUMOUR SYNDROMES OF THE FEMALE GENITAL TRACT)








BRCA1/2-associated hereditary breast and ovarian cancer syndrome Disease
Lynch syndrome Disease
Cowden syndrome Disease
Li-Fraumeni syndrome Disease
Peutz-Jeghers syndrome Disease
Ataxia-telangiectasia Disease
Carney complex Disease
DICER1 syndrome Disease
Ovarian dysgenesis Disease
Von Hippel-Lindau syndrome Disease
Hereditary leiomyomatosis and renal cell carcinoma Disease
Other genetic tumour syndromes of the female genital tract Disease